In the modern pharmaceutical industry, dry mix granulators have become core equipment for solid dosage manufacturing due to their efficiency, environmental friendliness, and suitability for heat-sensitive or moisture-sensitive materials. Based on technical characteristics and process adaptability, dry mix granulators commonly used in pharmaceutical factories are categorized into the following types:
1. Classification by Technical Characteristics
Binder-Free Dry Compacting Granulators: These machines directly compress dry powder raw materials into shape under high pressure without adding any binders. They are especially suitable for handling materials that are extremely sensitive to moisture or highly soluble in water, thereby eliminating the complex drying step required in wet granulation.
Integrated Regulating Granulators: These machines integrate the functions of material extrusion, crushing, and sizing into a single system, typically utilizing advanced roller compaction control technology to dynamically adjust to fluctuations in material physical properties. The granules produced exhibit better disintegration and dissolution profiles, and the equipment itself features a compact footprint that is easy to clean and maintain.
2. Classification by Process Adaptability
Crystalline Water Utilization Granulators: These machines directly utilize the material's own crystalline water to squeeze and form granules, offering a streamlined process and stable finished product quality. They are typically available in high/low pre-compression types as well as closed or open configurations, covering a wide capacity range of 5 to 400 kg/h .
TCM Dedicated Granulators: Specially engineered for Traditional Chinese Medicine (TCM) formula granules, these machines are designed to effectively handle complex chemical compositions, high stickiness, and the challenging issue of material sticking to the rollers.
3. General-Purpose Solid Dosage Granulators
General-purpose dry granulators, such as the LG series, are capable of producing both TCM and Western medicine granules. These versatile machines are suitable for multi-product R&D pilots as well as large-scale industrial manufacturing.
4. Custom Precision Component Machining Services
Whether dealing with binder-free high-pressure compaction, crystalline water extrusion, or highly viscous TCM granulation, different equipment models exhibit varying wear profiles and precision requirements for their core operating components.
Hansheng Automation supports the precise manufacturing of non-standard components based on client drawings. For all types of dry granulators operating in pharmaceutical factories, we provide precision custom machining services for core consumable accessories, including rollers, feeding screws, sizing blades, and non-standard screen frames. Whether you require wear-resistant rollers to withstand binder-free high-pressure compaction, or anti-sticking feeding screws to process viscous TCM raw materials, we can deliver high-quality, customized precision components through rigorous fit-tolerance control and surface modification treatments (such as electropolishing or specialized wear-resistant coatings), ensuring stable equipment operation under strict GMP-compliant standards.
