The high-efficiency wet mixer granulator is a core piece of equipment in solid dosage pharmaceutical production and fine chemicals. Its working principle primarily encompasses three interconnected physical stages: dry mixing, wet massing, and high-speed chopping.
The first stage involves high-intensity material mixing and the formation of a wet mass. Inside the cylindrical granulation bowl, powder materials and precisely injected liquid binders are forcibly pushed and tumbled by a bottom mixing impeller featuring a specialized hydrodynamic design. This intense three-dimensional mechanical agitation ensures a highly uniform distribution of multi-component materials and binders within a very short time. As mixing progresses, the materials develop excellent adhesion and plasticity, intertwining to form an optimal moist, plastic mass, which lays a solid foundation for the subsequent granulation process.
During this high-speed mixing and shearing process, the geometric shape, surface roughness, and dynamic balance precision of the bottom main impeller and the side-mounted high-speed chopper directly determine granule uniformity and the long-term operational stability of the equipment. We possess build-to-print customization capabilities and can execute precision machining for dedicated components of wet granulation machinery. Utilizing advanced multi-axis CNC machining centers, Hansheng Automation supports the exact manufacturing of various critical non-standard parts according to customer drawings, including complex mixing impellers, high-speed chopper blade assemblies, and highly sealed main shafts. By utilizing 316L or special high-strength stainless steel, we strictly control dynamic and static clearance tolerances at the micron level and apply pharmaceutical-grade polishing. This effectively prevents material adhesion in dead zones and avoids abnormal equipment wear.
The final stage is the critical granule cutting process. The formed wet mass is pushed toward the inner wall of the vessel by centrifugal force, where it is rapidly intercepted by the side-mounted high-speed chopper (flying blades). The rapidly rotating chopper blades forcefully cleave and finely cut the soft mass, ultimately breaking and shaping it into dense, wet granules with highly uniform particle sizes and excellent consistency. This highly efficient mechanical granulation process not only significantly shortens the cycle time but also fundamentally ensures high yields and batch-to-batch stability in subsequent fluid bed drying and tableting operations.
