Pharmaceutical equipment is mainly divided into five core categories: API (Active Pharmaceutical Ingredient) production equipment, formulation production equipment, pharmaceutical packaging equipment, pharmaceutical testing equipment, and auxiliary and supporting public works equipment.
I. API Production Equipment
(I) Specialized Equipment for Chemical APIs
1. Reaction Unit: Glass-lined reactor, stainless steel high-pressure reactor (operated by personnel with pressure vessel operation certificates), continuous flow microchannel reactor
2. Separation and Filtration Unit: Plate and frame filter press, disc centrifuge, tubular centrifuge, ultrafiltration/nanofiltration membrane filtration device
3. Drying Unit: Vacuum drying oven, fluidized bed dryer, centrifugal spray dryer, freeze dryer
4. Extraction and Concentration Unit: Multifunctional dynamic extraction tank, single-effect/multi-effect concentrator, falling film evaporator
5. Purification Unit: Crystallization tank, ion exchange column, preparative chromatography system
6. Aseptic Processing Unit: Aseptic air jet mill, double cone aseptic mixer
(II) Biopharmaceutical API Equipment
1. Fermentation Unit: Mechanically stirred fermenter, airlift fermenter, disposable bioreactor
2. Cell Culture Unit: Biosafety cabinet, CO₂ cell culture incubator, microcarrier culture system
3. Bioseparation and Purification Unit: Affinity chromatography column, gel filtration chromatography system, centrifugal extractor, high-pressure homogenizer
(III) Equipment for Traditional Chinese Medicine Raw Materials
1. Extraction Unit: Multifunctional traditional Chinese medicine extraction tank, percolation tank, static extraction tank
2. Concentration Unit: Single-effect/multi-effect traditional Chinese medicine concentrator
3. Pretreatment Unit: Traditional Chinese medicine slicer, traditional Chinese medicine pulverizer
II. Pharmaceutical Preparation Equipment
(I) Solid Dosage Form Production Equipment
1. Pretreatment Unit: Universal pulverizer, air jet mill, three-dimensional motion mixer
2. Granulation Unit: Wet granulator, dry granulator, fluidized bed granulation and coating machine
3. Forming Unit: High-speed rotary tablet press, fully automatic capsule filling machine, traditional Chinese medicine pill making machine
4. Post-processing unit: High-efficiency film coating machine, capsule polishing machine
(II) Liquid preparation production equipment
1. Liquid preparation unit: Concentrated preparation tank, diluted preparation tank, aseptic preparation system
2. Filling unit: Oral liquid filling and capping machine, large-volume parenteral solution filling machine
3. Sterilization unit: Water bath sterilizer, tunnel dry heat sterilizer
(III) Aseptic preparation production equipment
1. Ampoule washing, drying, filling and sealing integrated unit
2. Vial washing, drying, filling and sealing integrated unit
3. Pre-filled syringe filling line, lyophilized powder injection special freeze dryer
(IV) External preparation production equipment
1. Ointment tube filling and sealing machine, plaster coating machine, suppository filling machine
III. Pharmaceutical packaging equipment
1. Blister packaging equipment: Aluminum-plastic/aluminum-aluminum blister packaging machine
2. Bottle Packaging Production Line: Bottle unscrambler, ultrasonic bottle washer, filling machine, capping machine, self-adhesive labeling machine
3. Flexible Packaging Equipment: Stand-up pouch packaging machine, three-side seal granule packaging machine
4. Pharmaceutical Container Production Equipment: PET/PE medicine bottle injection molding and blow molding integrated machine
5. Bulk Packaging Equipment: Powder quantitative packaging machine
IV. Pharmaceutical Quality Testing Equipment
1. Physicochemical Analysis Equipment: High-performance liquid chromatograph, gas chromatograph, ultraviolet-visible spectrophotometer, electronic analytical balance
2. Microbiological Testing Equipment: Biosafety cabinet, constant temperature incubator, colony counter, sterility tester
3. Online Testing Equipment: Drug packaging integrity tester, metal foreign object detector, X-ray foreign object detector
4. Cleanroom Environment Testing: Dust particle counter, airborne bacteria sampler, anemometer
V. Auxiliary Supporting and Public Engineering Equipment
1. Cleanroom System: Air shower, pass-through window, high-efficiency air outlet, clean bench
2. Purified water and water for injection systems: Reverse osmosis unit, EDI electro-deionization equipment, multi-effect distillation water machine
3. Compressed air system: Oil-free air compressor, compressed air purification dryer
4. Material conveying system: Vacuum feeder, screw conveyor, dust-free belt conveyor
5. Cleaning and sterilization system: CIP in-place cleaning equipment, SIP in-place sterilization equipment
